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Agonist/Antagonist Opioid Analgesics. When a affected individual has Beforehand been given or is now undergoing a program of therapy with a pure opioid agonist analgesic like Dilaudid, agonist/antagonist analgesics like pentazocine, nalbuphine, butorphanol, and buprenorphine, needs to be used with caution.Respiratory depression. Respiratory depre